example:epshetsky@test.com, rek4@test.com, rajesh1239@test.com, mohanraj@test.com, sam@test.com, nithin@test.com, midhunvintech@test.com, karthickgm27@test.com, rajesh1239@test.com, mohanraj@test.com, nithin@test.com, I need results back like epshetsky@test.com, rek4@test.com, sam@test.com, nithin@test.com, midhunvintech@test.com, karthickgm27@test.com,   sort line with Edit -> Line Operations -> Sort Lines Lexicographically ascending do a Find / Replace: Find What: ^(.*\r?\n)\1+ Replace with: (Nothing, leave empty) Check Regular Expression in the lower left Click Replace All How it works: The sorting puts the duplicates behind each other. The find matches a line ^(.*\r?\n) and captures the line in \1 then it continues and tries to find \1 one or more times (+) behind the first match. Such a …