Remote Server returned ‘550 5.1.8 Access denied, bad outbound sender’
Solution:
–Non-Office 365 user use this https://sender.office.com (self-service delisting portal) to remove themselves from the blocked senders list.
–Office 365 user, as an admin you can unblock your blocked Office 365 email account via using Exchange admin center.
• Go to the EAC, navigate to protection > action center.
• Select the Search icon and enter the SMTP address of the blocked user.
• Click Unblock Account in the description pane.
• Click Yes to confirm the change.
For more detailed information, please refer to the article: Removing a user, domain, or IP address from a block list after sending spam email